胎牛血清是指胎牛血液凝固后，去除血漿中纖維蛋白原及某些凝血因子后分離出的淡黃色澄清液體，它是肉類加工業(yè)的一個(gè)副產(chǎn)品。
胎牛血清是細(xì)胞培養(yǎng)中用量較大的天然培養(yǎng)基，含有豐富的細(xì)胞生長(zhǎng)必須的營(yíng)養(yǎng)成分，具有極為重要的功能，一般添加比例為：5-20%。血清中含有各種氨基酸、維生素、無(wú)機(jī)物、脂類物質(zhì)等這些維持細(xì)胞生長(zhǎng)必須的營(yíng)養(yǎng)物質(zhì)，也含有胰島素、氫化可的松、地塞米松、bFGF、EGF、PDGF、轉(zhuǎn)鐵蛋白等可促進(jìn)細(xì)胞生長(zhǎng)的激素、生長(zhǎng)因子及結(jié)合蛋白。此外，血清還有解毒、緩沖、抑制蛋白酶活性等作用保護(hù)細(xì)胞不受傷害。
依科賽胎牛血清均采自非疫區(qū)的健康牛，經(jīng)無(wú)菌采集、批量混合、3級(jí)100 nm過(guò)濾器過(guò)濾分裝而成，不含支原體和BVDV、PI3、IBR、BTV等牛源病毒。
Zhong B et al. The Ubiquitin Ligase RNF5Regulates Antiviral Responses by Mediating Degradation of the Adaptor ProteinMITA. Volume 30, ISSUE 3, P397-407, March 20, 2009. Read more（PubMed: 19285439）
Li Q et al. CRISPR–Cas9-mediatedbase-editing screening in mice identifies DND1 amino acids that are criticalfor primordial germ cell development. Nature cell biology,2018. Read more（PubMed: 30718859）
Luo YL etal. Macrophage-Specific in Vivo Gene Editing Using Cationic Lipid-AssistedPolymeric Nanoparticles. ACS Nano 2018, 12, 994?1005.Read more（PubMed：29314827）
Du JZ et al. Smart Superstructureswith Ultrahigh pHSensitivity for Targeting Acidic Tumor. ACS Nano 2016, 10,6753?6761.Read more（PubMed：27244096）
Chen X et al. Long noncoding RNA LBCS inhibits self-renewal andchemoresistance of bladder cancer stem cells through epigenetic silencing ofSOX2. Clinical Cancer Research ,2018. Read more（PubMed：30397178）
Li HJ et al. Stimuli-responsiveclustered nanoparticles for improved tumor penetration and therapeuticefficacy. PNAS,2018. Read more（PubMed：27035960)
Li Y et al. ISG56 is anegative-feedback regulator of virus-triggered signaling and cellular antiviral response. PNAS, 2009,106(19): 7945-7950.Read more（PubMed：19416887)
Wang JL et al. The effect ofsurface poly(ethylene glycol) length on in vivo drug delivery behaviors ofpolymeric nanoparticles. Biomaterials 182（2018）104-113.Read more（PubMed：30114562)
